Wednesday, July 29, 2009

Metabolism Case Study

This just in from the National Center for Case Study Teaching in Science . . .

Our latest case study is “Why Is Patrick Paralyzed?” by Maureen Knabb, Department of Biology, West Chester University.

This clicker case introduces students to a rare genetic disease in which an enzyme is deficient in a critical metabolic pathway—the first step in aerobic respiration. This case challenges students to make connections between energy production, enzymes, and metabolic diseases.

Students are exposed to a real life story that serves as a basis for discussing the uses of energy-rich molecules and the importance of complex metabolic pathways catalyzed by protein enzymes.

Overall, students should appreciate the importance of each step in a metabolic pathway and the side effects as well as treatments that can emerge from discovering the underlying enzyme deficiency.


Teaching Notes:

Case Collection:
This module also includes a nice PowerPoint slide presentation.

If you use this case in your course, why not let us know how it works for you?

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