Monday, May 2, 2011

Video: Neutrophils to the Rescue

Have you seen this video from Science Videolab that shows fluorescent-stained neutrophils rushing toward the site of a tissue injury?

The clip actually strings together several videos showing bright green neutrophils rushing toward damaged cells in liver tissue (seen as bright red areas).  The narrator explains in simple terms what is going on and what it means in understanding what happens when tissue damage occurs.

This is a great FREE video to show your class when discussing any or all of these topics:
  • WBCs in general
  • Neutrophils
  • Immune response
  • Inflammation
  • Chemotaxis
Check out the video!
Want to know more?
Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation
Braedon McDonald et al.

15 October 2010: Vol. 330 no. 6002 pp. 362-366 DOI: 10.1126/science.1195491

[Research article that summarizes the discovery about how neutrophils use a multistep process to navigate toward noninfectious sites of tissue injury. ]
EDITORS' CHOICE: Immunology Inflammation Response in Living Color
Kristen L. Mueller
Sci. Signal., 19 October 2010 Vol. 3, Issue 144, p. ec324 DOI: 10.1126/scisignal.3144ec324
[Editor's summary of the processes described above]

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